Evening primrose oil is a rich and effective source of GLA and has shown positive outcomes in on a number of disorders such as menstrual problems, breast pains, rheumatoid arthritis and skin problems.
Biochemistry Evening primrose oil (EPO) is derived from the seeds of evening primrose plant. The oil contains a special fatty acid called gamma linolenic acid (GLA). GLA is one of the omega 6 fatty acids and is produced in the body from another fatty acid which is found in vegetable oils (linoleic acid). GLA is required by the body to produce substances knows as prostaglandins. Prostaglandins affect the immune system, circulation and menstrual cycles. Both lifestyle and psychological factors (such as stress, over consumption of alcohol, unhealthy diets, viruses, etc) can hinder the body's production of GLA.
Modes Of Action EPO constituents, namely GLA convert polyunsaturates into prostaglandins. Prostaglandins control and regulate numerous body processes, e.g. the prostaglandin, PGE takes part in regulating the nervous, cardiovascular and reproductive systems and maintaining healthy skin health whilst also having a role in other biological functions.
Supplemental Uses Blood pressure - research has shown that GLA from EPO noticeably reduces hypertension and may even prevent it from developing. Blood clotting - studies have shown that EPO can reduce platelets aggregation (blood clotting). High cholesterol - EPO lowers high serum cholesterol levels. Multiple Sclerosis (MS) - studies involving MS sufferers found that EPO brought abnormal levels of fatty acids in the brain back to normal within a few months of supplementation. Breast disease - research shows substantial reduction in benign breast disease. Premenstrual syndrome (PMS) - EPO is very successful in treating symptoms of PMS including abdominal pain, breast tenderness, swollen fingers and ankles, irritability, anxiety and depression. Rheumatoid arthritis - very good results were shown in patients suffering from rheumatoid arthritis, over 60% of patients withdraw from taking NSAIDS. Patients given EPO and fish oil combinations were found to be more effective. Skin conditions - positive results have been shown in studying carried out on a topic eczema and dermatitis sufferers.
Precautions / Adverse Effects Evening primrose oil can cause headaches, nausea or skin irritation when first taken.
Drug Interactions Epileptics should avoid EPO as the oil may induce certain temporal lobe epilepsy. Those taking medication for schizophrenia should avoid EPO supplements. Alpha linolenic acid (ALA) containing supplements have an inhibitory effect on the conversion of GLA and Linoleic acid into prostaglandins.
